Intermediates

Commercial

S.NoChemical NameCAS No.Being used in API
1Amino Acetaldehyde Dimethyl Acetal22483-09-6Dolutegravir
23-Amino-1-adamantanol702-82-9Vildagliptin
3(S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile207557-35-5Vildagliptin
45-Bromo-2-chlorobenzoic acid21739-92-4Dapagliflozin/Empagliflozin
54-bromo-1-chloro-2-(4-ethoxybenzyl)benzene461432-23-5Dapagliflozin
6Ethyl N-(2-pyridyl)-3-aminopropionate103041-38-9Dabigatran
74-(Methylamino)-3-nitrobenzoic acid HCl41263-74-5Dabigatran
83-[(3-Amino-4-Methylaminobenzoyl)-Pyridin-2-Ylamino]-Propionic Acid Ethyl Ester212322-56-0Dabigatran
9N(-4-cyano phenyl glycine)42288-26-6Dabigatran
104-Aminobenzimidamide Dihydrochloride2498-50-2Dabigatran
114-Amino-N'-hydroxybenzimidamide277319-62-7Dabigatran
123-[[[2-[[(4-Cyanophenyl) amino] methyl]-1-methyl-1H-benzimidazol-5-yl] carbonyl] pyridin-2-ylamino] propionic acid ethyl ester211915-84-3Dabigatran
13Dabigatran ethyl ester hydrochloride211914-50-0Dabigatran
14Ethyl 3-2-(4-amidinophenylamino) methyl)-1-methyl-N-(pyridin-2yl)-1H-benzo[d]imidazole-5-carboxamido) propanoate (N-2)429658-95-7Dabigatran
15Hexyl ((4-aminophenyl)(imino)methyl) carbamate Hydrochloride1307233-93-7Dabigatran
16Ethyl 3-(2-(chloromethyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate1307233-94-8Dabigatran
17ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl) amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate (N-1)211915-06-9Dabigatran
18(+)-(R)-4-propyl-4,5-dihydrofuran-2(3H)-one63095-51-2Brivaracetam
194-(4-fluorobenzoyl)butyric acid149437-76-3Ezetimibe
204-hydrazinobenzoic acid619-67-0Deferasirox
214-Hydroxy carbazole52602-39-8Carvedilol
225-amino-2-methylbenzenesulfonamide6973-09-7Pazopanib HCL
23Ethyl 7-bromo-2,2-dimethylheptanoate123469-92-1Bempedoic Acid
24p-Toluenesulfonyl methyl isocyanide (TosMIC)36635-61-7Bempedoic Acid
25Ethyl-6-bromo-2,2-dimethylhexanoate78712-62-6Bempedoic Acid
26Potassium 3-ethoxy-3-oxopropanoate6148-64-7Bempedoic Acid
27Diethyl acetone-1,3-dicarboxylate105-50-0Bempedoic Acid
28Diethyl Amino Malonate Hydrochloride13433-00-6Alprazolam/ Clorazepate
295-Bromo-2-Chloropyrimidine32779-36-5Macitentan/ Aprocitentan
302-Chloropyrimidine1722-12-9Piribedil/ Buspirone
315-Bromoindole10075-50-0Eletriptan
325-(2-Fluorophenyl)- 1H-Pyrrole- 3-carbaldehyde881674-56-2Vonoprazan Fumarate
333-Pyridine Sulfonyl chloride16133-25-8Vonoprazan Fumarate
345-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde881677-11-8Vonoprazan Fumarate
353-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride762240-92-6Sitagliptin
36Meldrum’s Acid2033-24-1Sitagliptin
374-formyl-3-methoxybenzonitrile21962-45-8Finerenone
384-amino-5-methylpyridin-2(1H)-one95306-64-2Finerenone
392-Cyanoethyl 3-oxobutanoate65193-87-5Finerenone
40(Z)-2-cyanoethyl 2-(4-cyano-2-methoxybenzylidene)-3-oxobutanoate1050477-39-8Finerenone
414-Methoxy-2-nitrophenol1568-70-3-
42Ethyl 3-amino-1H-pyrazole 4-carboxylate6994-25-8-
43Dimethyl (3-(3-chlorophenoxy)-2-oxopropy40665-94-9-
44(Formyl methylene) triphenyl phosphorane2136-75-6-
45Dimethyl (2-oxo-4-phenyl butyl) phosphonate41162-19-0-
464-Amino-N-(tert-butyl)benzamide93483-71-7-
472-Bromo-5-nitropyridine4487-59-6-
484-Pentyn-1-ol05/04/90-
49Methyl 4-aminonicotinate16135-36-7-


Under Development

S.NoChemical NameCAS No.Being used in API
11-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one1267610-26-3Apixaban
2(Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl) hydrazono) acetate27143-07-3Apixaban
37-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone22246-18-0Aripiprazole
41-Amino-4-cyclopentylpiperazine61379-64-4Rifapentine
51-methylpiperidine-4-carboxylic acid HCl71985-80-3Lasmiditan
65-Cyano Indole15861-24-2Vilazodone
7Acetyl Dapagliflozin461432-25-7Dapagliflozin
8(5-Bromo-2-chlorophenyl)(4-methoxyphenyl) methanone333361-49-2Empagliflozin
9(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-furan915095-89-5Empagliflozin
102-Aminoacetophenone551-93-9Linagliptin
118-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione666816-98-4Linagliptin
122-(chloromethyl)-4-methylquinazoline109113-72-6Linagliptin
13(R)-3-(boc-amino)piperidine309956-78-3Linagliptin
14(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride1062580-52-2Tofacitinib
153-Morpholino-1-[4-(2-oxo-1-piperidyl)phenyl]-5,6-dihydropyridin-2(1H)-one545445-44-1Apixaban
163-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one503615-03-0Apixaban
17Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate503614-91-3Apixaban
181-(2,2-Dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-2,5-pyridinedicarboxylic acid 2-methyl ester1335210-23-5Dolutegravir
195-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester147126-75-8Emtricitabine
202-(4-Nitrophenyl)ethyl amine Hydrochloride29968-78-3Mirabegeron
214,6-Dichloro-N-(methyl-d3)pyridazine-3-carboxamide1609393-89-6Mirabegeron
22(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanamide2102675-36-3Mirabegeron
232-(2-Aminothiazol-4-yl) acetic acid hydrochloride1218-69-5Mirabegeron
243-Iodo-6-nitroindazole70315-70-7Axitinib
252-mercapto-n-methylbenzamide20054-45-9Axitinib

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